Biostat System: Treatment for Low Back Pain

The Biostat System is a nonsurgical treatment for low back pain that involves the injection of a substance to seal tears and cracks that have formed in the intervertebral discs of the spine. These discs of the back are the cushions of our spine, and they can be squeezed to some extent, without coming apart, to allow the spine to be able to absorb the considerable pressures that we are putting on it as we work, sit, stand, and play. The disc is composed of tough and durable outer layer, called the annulus fibrosus. The disc is also composed of an inner, jelly-like layer called the nucleus pulposus. Together, these two layers are flexible enough to allow for some downward movement of the spine when weight is generated upon it, but is also tough enough to retain its essential shape and composition.

Pathology to the disc may occur when the structural integrity of its outer layer is compromised, or when the chemical composition of the materials in the inner layer changes. The outer ring of the disc, the annulus, is composed of several overlapping layers of tough fibrous tissue. Over time, or due to injury, the layers of the annulus may become worn out, frayed, or cracked. If these changes in the annulus continue, the disc may bulge outwards or herniated completely. If this disc bulge or herniation affects the nerve roots of the spine, the patient may then suffer from severe back pain. When the discs are degenerated to the point of causing the patient to have symptoms of back pain, the condition is known as internal disc disruption (IDD). The symptoms may include pain near the affected discs and nerves, as well as radiating pain to the hips, buttocks, groin and thighs. IDD is also referred to as "discogenic pain" because the source of the pain is in the disc itself.



The Biostat System involves a series on injections directly into the injured disc itself to seal the cracks that have developed in the annulus. The sealant in the injection seals the cracks in the disc, in the same way industrial sealants fill the cracks in driveways and concrete walls. During the procedure, a substance called BIOSTAT BIOLOGX Fibrin Sealant is injected to fill the tears and cracks that develop due to disc disease. This artificial sealant is designed to reduce discogenic pain by sealing painful disruptions, reducing inflammation, and enhancing tissue repair.

Scientific Rationale: Until recently doctors had to concede the fact that they could only treat discogenic pain indirectly, by strengthening the muscles around the degenerated discs rather than fix the discs themselves, for the patient to get better. Today, companies like the creators of the Biostat System seek to finally be able to repair the discs themselves. In tissues that are highly vascularized, the process from progresses from the following phases: Bleeding > Clot formation > Inflammation > Proliferation > Tissue Repair > Tissue Remodeling. The fibrin sealant of the Biostat System allows for the damaged tissues to be able to advance to the final stage of tissue remodeling.

Currently, this Biostat System, which you can learn more about by going to spinalrestoration.com, is currently in clinical trials, and is not widely available as a treatment for discogenic pain. You may want to log onto their website regularly for updates on the results of their clinical trials.